The alphanumeric moniker represents "Multi-Dimensional luxury ".In accordance with Honda, the MDX may be the best-selling three-row luxury crossover of them all, with cumulative U.S. sales likely to surpass 700,000 units before the finish of 2014. It has ranked whilst the second-best selling luxury crossover following the Lexus RX, which provides only two rows of seats. The Acura MDX, or Honda MDX as known in Japan and Australia (only the initial generation was imported), is a mid-size three-row luxury crossover, created by the Japanese automaker Honda under its Acura luxury nameplate since 2000.

The engine produced 290 horsepower and 267 lb-ft of torque and featured technologies such as Variable Cylinder Management (VCM), which allowed it to work in three different modes based on driving conditions to optimize fuel efficiency. The 2021 Acura MDX came designed with a 3.5-liter V6 engine. The MDX offered a smooth and responsive acceleration, allowing it to perform well both in city driving and on the highway. With regards to acceleration, the MDX was effective at going from 0 to 60 miles each hour in around 6.5 to 7 seconds, with regards to the specific model and drivetrain configuration.

Acura equipped 2025 MDX with Acura's latest safety technologies including adaptive cruise control, lane-keeping assist, and automatic emergency braking, which come together to mitigate potential collisions and help maintain safe distances on the road. Additionally, the 2025 Acura MDX offers an innovative traffic jam assist feature, enabling semi-autonomous driving capabilities in congested traffic situations. The Acura MDX features a surround-view camera system that gives a 360-degree view of the vehicle's surroundings, assisting with parking and maneuvering in tight spaces.

To cut back interior noise a traditional (PVB layered) windshield, acoustic entry way glass and thicker rear glass are utilized as well as triple sealed door openings. The MDX rides lower reducing its center of gravity. The seating H-point has been reduced and the steering gear ratio is 9% quicker for a more sporty feel. The inner reduced button clutter by the addition of a 7-inch touchscreen with haptic feedback, one more 8-inch screen is also standard. Advance package models include further noise reduction utilizing a thicker carpet base layer and front fender liners.

US sales began on June 20. The Acura MDX Prototype was unveiled at the 2013 North American International Auto Show, the production version was revealed at the New York Auto Show. Production began on May 2, 2013; vehicle assembly shifted from Ontario, Canada to Lincoln, Alabama.

However, some reviewers have noted that the third-row seats may be much more suited to children or smaller adults as a result of limited legroom. The driver's seat often includes power-adjustable settings, including lumbar support. The MDX typically offers spacious and comfortable seating for approximately seven passengers, with ample legroom and headroom in every three rows. The seats are often upholstered in high-quality materials, such as for instance leather, and are created to supply a supportive and luxurious driving experience.

The MDX also offers a variety of advanced technology features, including a user-friendly infotainment system and an array of safety and driver assistance features. The guts console often houses a prominent infotainment display that delivers usage of various functions, such as for example navigation, audio controls, and vehicle settings. Acura's infotainment system usually includes features like smartphone integration like CarPlay and Android Auto, Bluetooth connectivity, and multiple USB ports. The MDX typically includes a well-designed and high-quality interior. The third-row seats could be folded down to generate additional storage area when needed. Acura supplies a spacious cabin with comfortable seating for seven passengers. The MDX generally provides ample cargo space for its class. The materials found in the cabin are usually of good quality, giving the car reduced feel.

A 3.0-liter V6, 7-speed dual-clutch hybrid was added to the lineup, the trunk wheels are powered by twin electric motors and lithium-ion battery, and the hybrid is only for sale in all-wheel drive, while the standard variant of the 2017 Acura MDX began sales in Summer 2016, the hybrid will debut and begin sales in Spring 2017 (April 2017).

Each headlamp uses five separate LED sources with three useful for low-beam lighting and two for high-beam lighting. According to Acura the exterior is more aerodynamic reducing drag by 16% with the new model lapping Nürburgring 8 seconds faster than its predecessor. LED bumper mounted fog lamps are given as a dealer installed option. The headlights are Acura's Jewel Eye LED Headlights (first introduced on the RLX).

In 2003, the Honda MDX proceeded sale in Japan and Australia. In Japan, it filled a space once the Honda Horizon (also on the basis of the Trooper) was discontinued in 1999. The MDX has been the absolute most expensive crossover in Acura's lineup, except for the 2009-13 model years when Acura added a crossover to slot above the MDX, called the ZDX. The MDX was the initial crossover SUV to own third-row seating, and shares a platform with the Honda Pilot. The MDX was introduced as a 2001 model, replacing the slow-selling U.S.-only body-on-frame SLX, on the basis of the Isuzu Trooper. The Pilot seats eight, as the MDX seats seven, with two seating positions in the third row.